Protocol No. 79 is not a dietary supplement built around a trendy ingredient. It is a formula developed by two Doctors of Pharmacy, in which each active ingredient has been selected for its documented mechanism of action, its bioavailable form, and its complementarity with the others. Here is the reasoning behind each choice, and why their combination is more effective than the sum of their individual effects.
The starting point: imperfections have specific biological causes
Wrinkles and loss of firmness, dull complexion, dry and reactive skin, persistent redness, acne blemishes: these skin problems appear distinct, but they share common biological mechanisms. Collagen degradation. Weakening of the skin barrier. Chronic low-grade inflammation. Oxidative stress. Slowing of cellular metabolism.
Acting on only one of these mechanisms is not enough. This is the logic that guided the formulation of Protocol No. 79: simultaneously covering all the biological processes involved in skin quality, with active ingredients that mutually reinforce each other.
An intelligent formula does not look for the best ingredient. It looks for the best combination.
The active ingredients of Protocol No. 79 and the imperfections they target
Naticol® is a marine hydrolyzed collagen selected for the size of its peptides and the depth of its clinical documentation. Its low molecular weight peptides effectively cross the intestinal barrier and reach the dermal fibroblasts, where they trigger increased production of endogenous collagen. Clinical data shows +27% hydration and +26% elasticity in 60 days, and a measurable reduction in perioral wrinkles of 17%.
Standardized to 20% thymoquinone, black seed oil powder is the central piece of the formula. Thymoquinone simultaneously inhibits several inflammatory pathways: COX-2 and LOX enzymes, NF-kB factor. It neutralizes free radicals and modulates systemic immune response. Taken internally, it acts on the biological terrain of the entire organism, not just on the surface of the skin. It is what treats the deep causes of chronic skin reactivity.
Céramosides™ are phytoceramides standardized to 50% active phytoceramides, extracted from wheat seeds. Ceramides are the structural lipids of the skin barrier: they form the cement between epidermal cells that prevents water from evaporating and external aggressors from penetrating. With age and stress, their synthesis decreases and the barrier weakens. Taken internally, Céramosides™ replenish this lipid capital from within, with clinical data showing +35% skin ceramides and a significant improvement in suppleness and hydration.
Borage oil (Borago officinalis) is one of the most concentrated plant sources of gamma-linolenic acid (GLA), an essential fatty acid that the body does not synthesize in sufficient quantities. GLA is a precursor of anti-inflammatory prostaglandins that regulate the inflammatory response at the cellular membrane level. It nourishes skin cell membranes, reduces trans-epidermal water loss, and complements the anti-inflammatory action of thymoquinone on a different level: where black seed acts on signaling pathways, GLA acts at the level of the lipid membranes themselves.
Coenzyme Q10 plays a dual role in skin cells. On one hand, it is essential for mitochondrial energy production: without Q10, cells function slowly, their renewal is slower, and collagen synthesis is less efficient. On the other hand, it is one of the most powerful fat-soluble antioxidants in the body, protecting cell membranes against oxidative stress. Its natural production declines by 40% between 20 and 40 years of age, precisely when the first signs of aging appear. In the formula, it amplifies the action of Naticol® by ensuring that fibroblasts have the necessary energy to produce collagen stimulated by the peptides.
Vitamin E is the benchmark fat-soluble antioxidant for protecting cell membranes. It acts on membrane phospholipids by protecting them from lipid peroxidation, a process by which free radicals degrade the structural fats of membranes. In the formula, it works in tandem with Coenzyme Q10: after neutralizing a free radical, vitamin E is regenerated by Q10, allowing them to provide continuous and synergistic protection. It also protects thymoquinone and GLA from oxidation within the formula itself.
Selenium is not a direct antioxidant: it is an essential cofactor for the body's natural antioxidant enzymes, including glutathione peroxidase and thioredoxin reductase. These enzymes form the first line of cellular defense against oxidative stress. Without sufficient selenium, the entire antioxidant network of the body is compromised, including the effectiveness of Coenzyme Q10 and vitamin E. At 100% of the daily reference intake, the selenium in Protocol No. 79 ensures that this network functions at full capacity.
Vitamin D3 is present in the formula at 400% of the daily reference intake. Beyond its well-known role in the skeletal and immune systems, vitamin D3 is involved in regulating the differentiation cycle of keratinocytes, the main cells of the epidermis. It contributes to normal skin renewal and the modulation of the cutaneous inflammatory response. Vitamin D deficiency is common in Europe, especially outside the summer months, and directly impacts skin quality and resistance.
Why this combination is more effective than its parts
What distinguishes Protocol No. 79 from a mere stacking of active ingredients is the coherence of their interaction. Each ingredient has been chosen not only for its own effects but for its complementarity with the others.
Naticol® stimulates fibroblasts to produce collagen. Coenzyme Q10 provides these same fibroblasts with the mitochondrial energy needed to do so efficiently. Vitamin E and selenium protect newly synthesized collagen from oxidative degradation. Thymoquinone from black seed reduces systemic inflammation that would activate metalloproteinases, enzymes that specifically degrade collagen. GLA from borage complements this anti-inflammatory action at the membrane level. Céramosides™ rebuild the skin barrier so that the effects of the entire formula can be expressed on skin capable of showing them.
This is no coincidence. It is the result of a formulation conceived by Doctors of Pharmacy who understand skin biology and the mechanisms of action of each active ingredient.
- Wrinkles & loss of firmness Naticol® + CoQ10 + vitamin E + selenium work together on the production, protection, and preservation of skin collagen.
- Dry skin & weakened barrier Céramosides™ + GLA rebuild the skin's lipid film and reduce water loss through two complementary mechanisms.
- Redness & reactive skin Black seed + GLA modulate systemic and membrane inflammation that maintains chronic skin reactivity.
- Inflammatory acne Black seed acts on the inflammatory terrain that promotes outbreaks. GLA regulates the local inflammatory response.
- Dull complexion & aging CoQ10 + vitamin E + selenium + vitamin D3 form a complete antioxidant network that protects skin cells and supports their renewal.
What this changes in expected results
A single-active formula produces results on one axis only. A collagen supplement alone improves elasticity but does not treat reactivity. A natural anti-inflammatory alone soothes but does not rebuild. A combined and coherent formula like Protocol No. 79 produces results on several axes simultaneously, leading to a more comprehensive visible transformation of skin quality.
In the first few weeks, skin comfort and reduced reactivity often improve, thanks to the anti-inflammatory action of black seed and GLA. Between four and eight weeks, hydration and skin radiance progress, reflecting the action of Céramosides™ and CoQ10. After two to three months, the effects on elasticity, density, and fine lines become measurable, at the rate of natural skin collagen renewal.
Protocol No. 79 does not target a skin problem. It targets the biological mechanisms behind all skin problems.
Frequently asked questions about Protocol No. 79
Protocol No. 79 contains thymoquinone from black seed and essential fatty acids GLA, two active ingredients with documented anti-inflammatory properties that act on the systemic mechanisms of acne. These active ingredients do not treat acne like a dermatological medication but help reduce the inflammatory terrain that promotes and maintains it.
Naticol® is a type I marine hydrolyzed collagen whose low molecular weight peptides stimulate dermal fibroblasts to produce more endogenous collagen. Clinical data for this ingredient show +27% hydration, +26% elasticity, and a 17% reduction in perioral wrinkles after 60 days of regular supplementation.
Protocol No. 79 is designed to act on the main skin imperfections common to all skin types: wrinkles and lack of elasticity, dryness and weakened barrier, redness and reactivity, dull complexion, acne, and inflammatory blemishes. Its multi-active formulation allows it to address these different issues simultaneously.
Protocol No. 79 should be taken with a meal containing dietary fats, with a large glass of water. The presence of dietary lipids promotes the absorption of fat-soluble active ingredients such as thymoquinone, GLA, and Coenzyme Q10. Daily regularity is essential to achieve lasting results over time.
